FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\groB88
Open Close
General Information
Symbol
Dmel\groB88
Species
D. melanogaster
Name
FlyBase ID
FBal0031415
Feature type
allele
Associated gene
Dmel\gro
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Heitzler et al., 1996)
Mutagen
ethyl methanesulfonate
(Schrons et al., 1992, Ziemer et al., 1988)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Ziemer et al., 1988)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      macrochaeta & scutum

      (Heitzler et al., 1996)

      microchaeta & scutum

      (Heitzler et al., 1996)
      Detailed Description
      Statement
      Reference

      Clones fail to differentiate epidermis. Microchaetes are densely packed and adjacent to one another. Macrochaetes are present as dense tufts of abnormal bristles.

      (Heitzler et al., 1996)

      Embryos homozygous for lethal gro mutations show highly variable neurogenic phenotypes with incomplete penetrance. This allele shows a weak neurogenic phenotype over Df(3R)Espl4.

      (Schrons et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      E(spl)m8-HLH1, groB88 has lethal phenotype

      (Ziemer et al., 1988)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E(spl)B88
      E(spl)r8
      (Lindsley and Zimm, 1992)
      groB88
      l(3)B88
      (Ziemer et al., 1988)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0003329
      References (5)