FB2026_03 , released September 17, 2026
Allele: Dmel\htsRK
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General Information
Symbol
Dmel\htsRK
Species
D. melanogaster
Name
FlyBase ID
FBal0031509
Feature type
allele
Associated gene
Dmel\hts
Associated Insertion(s)
P{ry11}htsRK
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Yue and Spradling, 1992)
Mutagen
P-element activity
(Yue and Spradling, 1992)
Progenitor genotype
Associated Insertion(s)
P{ry11}htsRK
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females produce egg chambers with less than 15 nurse cells and these egg chambers usually degenerate before completing oogenesis. Most egg chambers lack an oocyte. Ring canals in cysts and egg chambers are reduced in number and have deformed outer rings. Phalloidin staining revealed that the abnormal ring canals were deficient in actin. Homozygotes show reduced viability and rough eyes.

      (Yue and Spradling, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Dysgenesis induced revertants have normal viability, are fertile and have no egg chamber defects.

      (Yue and Spradling, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      htsRK
      Name Synonyms
      Secondary FlyBase IDs
        References (1)