FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ord3
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General Information
Symbol
Dmel\ord3
Species
D. melanogaster
Name
FlyBase ID
FBal0032312
Feature type
allele
Associated gene
Dmel\ord
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Miyazaki and Orr-Weaver, 1992)
Progenitor genotype
Cytology
Description

Mutation of the donor splice site of the third intron.

(Bickel et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:23,272,726..23,272,726 [-]
Nucleotide change:

G23272726A

Comment:

GT to AT mutation in the splice donor site

(Bickel et al., 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Meiotic recombination is reduced but not absent. Mutation does not interfere with ord4 activity: does not show negative complementation.

      (Bickel et al., 1997)

      Transmission rate of Dp(1;f)J21A through females to progeny is 28%, ord mutation has no effect on transmission. Mutation has no effect on Dp(1;f)J21A transmission in males.

      (Cook et al., 1997)

      Level of chromosome missegregation in homozygous females is 60.2%.

      (Bickel et al., 1996)

      Increased frequency of premature sister chromatid disjunction: homozygous females are fertile.

      (Miyazaki and Orr-Weaver, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      ord1/ord3 has phenotype, non-suppressible by anon-59Da3.6RR

      (Bickel et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ord1/ord3 is rescued by ordEGFP

      (Balicky et al., 2002)

      ord1/ord3 is rescued by ord+t6.3

      (Bickel et al., 1996)

      ord1/ord3 is rescued by ord+tD39

      (Bickel et al., 1996)
      Not rescued by

      ord1/ord3 is not rescued by ordD26

      (Bickel et al., 1996)

      ord1/ord3 is not rescued by ord7.3BPΔ

      (Bickel et al., 1996)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong allele.

      (Miyazaki and Orr-Weaver, 1992)

      Does not interact with ord4 to alter the female meiotic chromosome segregation phenotype.

      (Bickel et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ord3
      Name Synonyms
      Secondary FlyBase IDs
        References (6)