FB2025_02 , released April 17, 2025
Allele: Dmel\rnroe-KE55
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General Information
Symbol
Dmel\rnroe-KE55
Species
D. melanogaster
Name
FlyBase ID
FBal0032607
Feature type
allele
Associated gene
Dmel\rn
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Brand and Campos-Ortega, 1990)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Allele shows both "rn" (rotund) and "roe" (roughened eye) phenotypes. Transheterozygotes with Df(3R)Scx4 show defects in distal appendages and roughness of the compound eye.

      (Brand and Campos-Ortega, 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      rnroe-KE55/rn[+] is an enhancer of phenotype of Nspl-1

      (Brand and Campos-Ortega, 1990)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhancement of the Nspl-1 phenotype is due to haploinsufficiency of the rn locus, not allele-specific interactions.

      (Brand and Campos-Ortega, 1990)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      rnroe-KE55
      roeKE55
      Name Synonyms
      Secondary FlyBase IDs
        References (1)