FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\scaUM2
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General Information
Symbol
Dmel\scaUM2
Species
D. melanogaster
Name
FlyBase ID
FBal0032664
Feature type
allele
Associated gene
Dmel\sca
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Lee et al., 1998)
Mutagen
ethyl methanesulfonate
(Hu et al., 1995, Baker et al., 1992, Mlodzik et al., 1990)
Progenitor genotype
Cytology
Description

Missense mutation.

(Baker and Zitron, 1995)

Amino acid replacement: D654N. Nucleotide substitution: G2093A. Residue within the conserved DXDXD motif present in all FReDs.

(Hu et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:12,800,571..12,800,571 [+]
Nucleotide change:

G12800571A

Reported nucleotide change:

G2093A

Amino acid change:

D679N | sca-PA; D679N | sca-PB

Reported amino acid change:

D654N

(Hu et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      scaUM2/scaBP2 flies have extra thoracic bristles.

      (Lee et al., 1998)

      The number of R8 cells is increased in scaBP2/scaUM2 Nl1N-ts1 or scaUM2/scaUM2 Nl1N-ts1 double mutants compared to Nl1N-ts1 single mutants, and no regular array of R8 cells can be seen.

      (Baker and Zitron, 1995)

      Mutant eye discs are abnormal. Mutant adults have rough eyes.

      (Baker et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      scaUM2
      Name Synonyms
      Secondary FlyBase IDs
        References (7)