FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tsh1
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General Information
Symbol
Dmel\tsh1
Species
D. melanogaster
Name
FlyBase ID
FBal0032942
Feature type
allele
Associated gene
Dmel\tsh
Associated Insertion(s)
P{A92}tsh1
Carried in Construct
Also Known As
R30b, tsh-lacZ
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Rauskolb et al., 1995, Fasano et al., 1991, Fasano et al., 1989)
Progenitor genotype
P{A92}A
(Fasano et al., 1989)
Associated Insertion(s)
P{A92}tsh1
Cytology
Description

P-element insertion into tsh.

(Rauskolb et al., 1995)

Insertion of P{A92} within the 5' flanking region of tsh.

(Fasano et al., 1991)
Allele components
Component
Use(s)
Inserted element
P{A92}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous viable, adults display a mild phenotype: twinning of the anterior scutellar bristles. Trans-heterozygotes with Df(2L)TW161 are semi-lethal: escapers have malformed prothoracic trochanters. Neuronal defects: disruption or deletion of ventral groups of neurons in the trunk region and misrouting of axons towards the head.

      (Fasano et al., 1991)

      Thorax sense organs are found adjacent to the malformed Keilins organs suggesting a partial transformation of the thoracic segments to the labial segment.

      (Fasano et al., 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tsh1
      tshR30b
      (Rauskolb et al., 1995)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0046623
      References (3)