FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vasHE1
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General Information
Symbol
Dmel\vasHE1
Species
D. melanogaster
Name
FlyBase ID
FBal0033077
Feature type
allele
Associated gene
Dmel\vas
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12, Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description

Amino acid replacement: R170S.

(Lasko, 2000.2.1)

Amino acid replacement: R170S. Nucleotide substitution is of AGT for AGA, N terminal to the 425 amino stretch that is highly similar among DEAD-box proteins.

(Liang et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:15,072,435..15,072,435 [+]
Nucleotide change:

A15072435T

Reported nucleotide change:

A?T

Amino acid change:

R170S | vas-PA; R170S | vas-PB; R170S | vas-PC

Reported amino acid change:

R170S

Comment:

Lasko, 2000.2.7, personal communication

(Liang et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Normal eggs. Embryos lack polar granules, pole cells and abdominal segments.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      solounspecified

      (Yan et al., 2010)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HE1
      (Yan et al., 2010)
      vasHE1
      (Lasko, 2000.2.1)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)