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General Information
Symbol
Dmel\Cdc37+t9.5
Species
D. melanogaster
Name
FlyBase ID
FBal0033497
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Linked to:
SstII-KpnI restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

DNA fragment contains full-length Cdc37 and the 5' 780bp genomic region of Patj, which corresponds to the N-terminal 260 aa of Patj protein.

Contained within a 9.5kb genomic KpnI-SacII fragment.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Eyes from newly eclosed flies homozygous for the mutant chromosome Patj[synhypo], which consists of Df(3L)MY10 carrying the rescue fragments α-SpecUbi-p63E.PP, dltUbi-p63E.PP and Cdc37+t9.5 (which rescues Cdc37 and the N'terminal of Patj), show malformation or loss of photoreceptor rhabdomeres at low frequency. Eyes from 7 day old mutants reveal severe disruption in the proximal region toward the basement membrane of the retina. Rhabdomeres show a graded phenotype, abnormally shaped or missing in the proximal half of the eye but relatively well organised in the distal region towards the surface of the eye.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Cdc37+t9.5
Name Synonyms
Secondary FlyBase IDs
    References (6)