FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cdc37+t9.5
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General Information
Symbol
Dmel\Cdc37+t9.5
Species
D. melanogaster
Name
FlyBase ID
FBal0033497
Feature type
allele
Associated gene
Dmel\Cdc37
Associated Insertion(s)
Carried in Construct
P{pW8K/ScII}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Cutforth and Rubin, 1994)
wild_type
(Cutforth and Rubin, 1994)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Cutforth and Rubin, 1994)
wild_type
(Cutforth and Rubin, 1994)
Mutagen
in vitro construct
(Cutforth and Rubin, 1994)
Progenitor genotype
Carried in construct
P{pW8K/ScII}
Cytology
Description

DNA fragment contains full-length Cdc37 and the 5' 780bp genomic region of Patj, which corresponds to the N-terminal 260 aa of Patj protein.

(Nam and Choi, 2006)

Contained within a 9.5kb genomic KpnI-SacII fragment.

(Cutforth and Rubin, 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Cdc37
Encoded product / tool
Cdc37
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3L:1,790,859..1,799,932 [+]
Linked to:
SstII-KpnI restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator

(Cutforth and Rubin, 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eyes from newly eclosed flies homozygous for the mutant chromosome Patj[synhypo], which consists of Df(3L)MY10 carrying the rescue fragments α-SpecUbi-p63E.PP, dltUbi-p63E.PP and Cdc37+t9.5 (which rescues Cdc37 and the N'terminal of Patj), show malformation or loss of photoreceptor rhabdomeres at low frequency. Eyes from 7 day old mutants reveal severe disruption in the proximal region toward the basement membrane of the retina. Rhabdomeres show a graded phenotype, abnormally shaped or missing in the proximal half of the eye but relatively well organised in the distal region towards the surface of the eye.

      (Nam and Choi, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Cdc37+t9.5
      Name Synonyms
      Secondary FlyBase IDs
        References (6)