FB2025_02 , released April 17, 2025
Allele: Dmel\E(spl)m8-HLH+t2.8
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General Information
Symbol
Dmel\E(spl)m8-HLH+t2.8
Species
D. melanogaster
Name
FlyBase ID
FBal0033647
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
P{E(spl)m8-HLH+2.8}
Key Links
Genomic Maps

Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Schrons et al., 1992)
Progenitor genotype
Carried in construct
P{E(spl)m8-HLH+2.8}
Cytology
Description

Contained within a 2.8kb ClaI genomic fragment.

(Schrons et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
E(spl)m8-HLH
Encoded product / tool
E(spl)m8-HLH
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:26,038,976..26,041,745 [+]
Linked to:
ClaI-ClaI restriction fragment
(Schrons et al., 1992)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(spl)m8-HLH+t2.8 is an enhancer of eye phenotype of Nspl-1

      (Nagel et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A single copy has no effect but two copies of HLHm7+t5.6 enhances the eye phenotype seen in Nspl-1 flies.

      (Nagel et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E(spl)+t2.8
      E(spl)m8-HLH+t2.8
      Name Synonyms
      Secondary FlyBase IDs
        References (2)