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General Information
Symbol
Dmel\Ras85DQ13.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0033979
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Expression of an activated Ras85D is driven by an Hsp70 promoter.

Hsp70 promoter drives expression of Ras85D that has been mutated to carry a G13Q amino acid replacement.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Ras85DQ13.hs using heat shock results in a high frequency of defects in the dorsal cuticle.

Expression in the embryo inhibits, to large extent, naturally occurring cell death. Apoptosis only remains in the CNS.

Partial rescue of tracheal migration defect in btl homozygotes.

One copy of the P{hs-Ras1Q13} construct causes a low hatching rate. Some unhatched embryos display a range of abdominal defects and duplicated filzkorper material. Other display defects in head involution, germband retraction or dorsal/ventral patterning.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Border cell migration defect is rescued by Scer\GAL4hs.PB-mediated expression of slboScer\UAS.cLa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ras85DQ13.hs
Name Synonyms
Secondary FlyBase IDs
    References (5)