FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\glES5
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General Information
Symbol
Dmel\glES5
Species
D. melanogaster
Name
FlyBase ID
FBal0034720
Feature type
allele
Associated gene
Dmel\gl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Carthew et al., 1994)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Clonal analysis reveals homozygous ommatidia have abnormal photoreceptors.

        (Carthew et al., 1994)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        glES5 is a suppressor of visible phenotype of sinaGMR.PN

        (Neufeld et al., 1998)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        glES5 is an enhancer of phenotype of sina4

        (Carthew et al., 1994)
        Suppressor of
        Statement
        Reference

        glES5 is a suppressor of eye phenotype of sinaGMR.PN

        (Neufeld et al., 1998)

        glES5 is a suppressor of eye phenotype of Ras85DV12.sev

        (Carthew et al., 1994)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Dominant enhancer of the sina4 homozygous mutant phenotype, photoreceptor cell R7 is missing and one or two outer photoreceptor cells. Dominant suppression of Ras85DV12.sev phenotype, eyes are restored to a nearly wild type appearance.

        (Carthew et al., 1994)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        E(sina)5
        (Neufeld et al., 1998)
        E(sina)5L1
        (Carthew et al., 1994)
        glES5
        Name Synonyms
        Secondary FlyBase IDs
          References (2)