FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\opahs.PB
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General Information
Symbol
Dmel\opahs.PB
Species
D. melanogaster
Name
heat shock construct of Benedyk
FlyBase ID
FBal0035311
Feature type
allele
Associated gene
Dmel\opa
Associated Insertion(s)
Carried in Construct
P{HSopaC}
Key Links
Transgenic product class
frameshift_truncation
(Benedyk et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
frameshift_truncation
(Benedyk et al., 1994)
Mutagen
in vitro construct
(Benedyk et al., 1994)
Progenitor genotype
Carried in construct
P{HSopaC}
Cytology
Description

Hsp70 promoter drives the expression of opaC cDNA which lacks the C residue at position 1781 resulting in a frameshift at amino acid residue 496, shortening the predicted protein by 100 amino acids.

(Cimbora and Sakonju, 1995)

opaC cDNA, which carries a frameshift mutation resulting in a truncated protein, is expressed from an Hsp70 promoter.

(Benedyk et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
opa
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      opahs.PB partially rescues opa2

      (Benedyk et al., 1994)

      opahs.PB partially rescues opa1

      (Benedyk et al., 1994)
      Comments

      Partially rescues the pair rule phenotype of opa1 and opa2 when subjected to a 20min heat shock during cellularization.

      (Benedyk et al., 1994)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Partial restoration of ectodermal segmentation of opa1 and opa2 embryos, the encoded protein retains some wild type functions.

      (Cimbora and Sakonju, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      opahs.PB
      Name Synonyms
      heat shock construct of Benedyk
      Secondary FlyBase IDs
        References (2)