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General Information
Symbol
Dmel\wgS84
Species
D. melanogaster
Name
FlyBase ID
FBal0036004
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Deletion in the DNA encoding the carboxy-terminus of the wg protein.

    C-terminal deletion.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Loss of function allele at 25oC and an antimorphic allele at 17oC. At 17oC wgSp-1/wgS84 flies are wild type. Combination of wgspd-fg wgS84 at 25oC causes alular etching. At 17oC this etching phenotype is enhanced and causes loss of ventral structures, truncations and complete loss of legs. wgspd-fg wgSp-m2/wgS84 flies shifted to 17oC postembryonically exhibit further wing etching, leg disturbances, loss of terminal structures of the proboscis, macrochaetes and microchaetes on the notum, one or both antenna and abdominal sternites. wgspd-fg wgSp-1/wgS84 flies shifted to 17oC postembryonically also show enhancement of the wing etching phenotype, occasional loss of one or both antennae and dorsocentral rows of microchaetes, occasional sternites are missing but no sign of either the leg phenotypes or the aDC macrochaetae loss. At 25oC wgSp-1/wgS84 and wgspd-fg wgSp-1/wgS84 flies lose aDC macrochaetes.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhancer of
    Statement
    Reference

    wgS84 is an enhancer of phenotype of SerCS94

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Dominant enhancer of Ser null mutations at 17oC, flies die as pupae with nicks in the wing margin.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Protein is secreted. Antimorphic at 17oC, null at 25oC. Has an antimorphic effect on N at 17oC. Shows strong allele-specific interaction with Nnd-2, and no interaction with NM1.

    Null at 25oC and an antimorph at 17oC.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    wgS84
    Name Synonyms
    Secondary FlyBase IDs
      References (3)