FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Shs.sev
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General Information
Symbol
Dmel\Shs.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0039012
Feature type
allele
Associated gene
Dmel\S
Associated Insertion(s)
Carried in Construct
P{sE-Star}
Key Links
Transgenic product class
cDNA
(Kolodkin et al., 1994)
wild_type
(Kolodkin et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kolodkin et al., 1994)
wild_type
(Kolodkin et al., 1994)
Mutagen
in vitro construct
(Kolodkin et al., 1994)
Progenitor genotype
Carried in construct
P{sE-Star}
Cytology
Description

Construct: A 4kb fragment containing the entire S cDNA is expressed from two sev enhancers linked to an Hsp70 promoter.

(Kolodkin et al., 1994)
Allele components
Component
Use(s)
Encoded product / tool
S
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eyes are rough, probably due to defects in cone and pigment cells. Ommatidia have extra R cells which may resemble R7 or R1-6.

      (Kolodkin et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Shs.sev has visible phenotype, enhanceable by sty[+]/styS73

      (Casci et al., 1999)

      Shs.sev has visible phenotype, enhanceable by sty[+]/styS88

      (Casci et al., 1999)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Shs.sev has eye phenotype, enhanceable by sty[+]/styS73

      (Casci et al., 1999)

      Shs.sev has eye phenotype, enhanceable by sty[+]/styS88

      (Casci et al., 1999)
      Suppressor of
      Statement
      Reference

      Shs.sev is a suppressor of photoreceptor cell R7 phenotype of SosJC2, sev6

      (Kolodkin et al., 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses the R7 defect of sev6/Y; SosJC2/+.

      (Kolodkin et al., 1994)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Shs.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (3)