FB2026_02 , released June 18, 2026
Allele: Dmel\dac2
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General Information
Symbol
Dmel\dac2
Species
D. melanogaster
Name
FlyBase ID
FBal0039228
Feature type
allele
Associated gene
Dmel\dac
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Mardon et al., 1994)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: E816K. Nucleotide substitution: G?A.

    (Tavsanli et al., 2004)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:16,469,229..16,469,229 [-]
    Nucleotide change:

    G16469229A

    Reported nucleotide change:

    G?A

    Amino acid change:

    E807K | dac-PA; E816K | dac-PB; E800K | dac-PC; E809K | dac-PD; E807K | dac-PF; E798K | dac-PG

    Reported amino acid change:

    E816K

    (Tavsanli et al., 2004)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant animals have eyes about three quarters the size of wild-type size, and legs three quarters the size of normal, with tibial tarsal fusions.

        (Tavsanli et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Other
        Statement
        Reference

        EgfrE3, dac2 has eye phenotype

        (Mardon et al., 1994)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Modifies the EgfrE3 mutant eye phenotype.

        (Mardon et al., 1994)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        dac2
        Name Synonyms
        Secondary FlyBase IDs
          References (3)