FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gclHsp83.PJ
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General Information
Symbol
Dmel\gclHsp83.PJ
Species
D. melanogaster
Name
Heat shock protein 83 promoter construct of Jongens
FlyBase ID
FBal0039362
Feature type
allele
Associated gene
Dmel\gcl
Associated Insertion(s)
Carried in Construct
P{hg(hsp83/gcl)}
Key Links
Transgenic product class
wild_type
(Jongens et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Jongens et al., 1994)
Mutagen
in vitro construct
(Jongens et al., 1994)
Progenitor genotype
Carried in construct
P{hg(hsp83/gcl)}
Cytology
Description

Expression of gcl coding region and 3' untranslated region (3'UTR) is driven by an Hsp83 promoter.

(Jongens et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp83
Encoded product / tool
gcl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat shock causes generation of supernumerary pole cells but these cannot be detected after stage 14 embryos when the pole cells coalesce in the embryonic gonad. Hoescht-staining demonstrates a large number of the pole cells fall through the somatic cell layer, lose their plasma membrane and leave behind a mass of chromatin. The resulting embryos develop into morphologically normal fertile adults. Over expression in early embryos leads to a distinct nuclear morphology and earlier onset of mitotic asynchrony of the pole bud nuclei.

      (Jongens et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      gclHsp83.PJ rescues gclrev390

      (Robertson et al., 1999)
      Comments

      Addition of this construct to flies homozygous for Df(2R)cmp44E-rev390, also carrying one copy of cmp44E+t8.5, rescues the maternal effect pole cell and pole bud phenotypes seen in these flies.

      (Robertson et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Overexpression of gcl in the germline.

      (Jongens et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      gclHsp83.PJ
      Name Synonyms
      Heat shock protein 83 promoter construct of Jongens
      (Jongens et al., 1994)
      Secondary FlyBase IDs
        References (3)