FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sevhs.PBa
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General Information
Symbol
Dmel\sevhs.PBa
Species
D. melanogaster
Name
heat shock construct a of Basler
FlyBase ID
FBal0039891
Feature type
allele
Associated gene
Dmel\sev
Associated Insertion(s)
Carried in Construct
P{sev2}
Also Known As
hsp-sev
Key Links
Transgenic product class
cDNA
(Basler and Hafen, 1989)
wild_type
(Basler and Hafen, 1989)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Basler and Hafen, 1989)
wild_type
(Basler and Hafen, 1989)
Mutagen
in vitro construct
(Basler and Hafen, 1989)
Progenitor genotype
Carried in construct
P{sev2}
Cytology
Description

8.2kb sev cDNA is expressed from an Hsp70 promoter.

(Basler and Hafen, 1989)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
sev
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      sevhs.PBa rescues sev14

      (Basler and Hafen, 1989)

      sevhs.PBa rescues sev14

      (Basler and Hafen, 1989)

      sevhs.PBa rescues sev14

      (Basler et al., 1989)
      Comments

      Heat shock every 4 hours for 30 minutes starting 24 hours before and lasting 12 hours after the white prepupal stage can completely rescue the sev14 mutant phenotype. Heat shock every 8 hours causes a minor portion of ommatidia lacking R7 cells, heat shock every 12 hours causes well defined stripes of sev- ommatidia and wild type ommatidia. Induction of sev 12 hours after white prepupae formation is the last time point that rescues anterior most ommatidia columns.

      (Basler and Hafen, 1989)

      Mutant phenotype can be completely rescued by sevhs.PBa after heat shock every 6 hours for 30 minutes. Heat shock every 12 hours causes alternating stripes of sev- ommatidia and wild type ommatidia.

      (Basler and Hafen, 1989)

      Induction of the construct every 4 hours for 30 minutes completely rescues the sev14 mutant phenotype. Rescue is not seen without heat shock.

      (Basler et al., 1989)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Basler and Hafen.

      (Basler et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      sevhs.PBa
      Name Synonyms
      heat shock construct a of Basler
      (Basler and Hafen, 1989)
      type A hsp-sev
      (Basler et al., 1989)
      Secondary FlyBase IDs
        References (6)