FlyBase Allele Report: Dmel\slp1[A509]

General Information

Symbol

Dmel\slp1^A509

Species

D. melanogaster

Name

FlyBase ID

FBal0039917

Feature type

allele

Associated gene

Dmel\slp1

Associated Insertion(s)

P{lArB}slp1^A509

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Grossniklaus et al., 1992)

Mutagen

P-element activity

(Grossniklaus et al., 1992)

Progenitor genotype

Associated Insertion(s)

P{lArB}slp1^A509

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lArB}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:3,825,634..3,825,634 [+]

(Grossniklaus et al., 1992)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage

(Grossniklaus et al., 1992)

some die during embryonic stage

(Grossniklaus et al., 1992)

Phenotype Manifest In

cuticle

(Grossniklaus et al., 1992)

hypostomal sclerite

(Grossniklaus et al., 1992)

lateral process of cephalopharyngeal skeleton

(Grossniklaus et al., 1992)

ventral denticle belt

(Grossniklaus et al., 1992)

ventroposterior arm of apodeme of rostrum-haustellum joint

(Grossniklaus et al., 1992)

Detailed Description

Statement

Reference

Homozygotes display a weak cuticle phenotype affecting the odd numbered segments. Lethal when heterozygous with slp1³ and Df(2L)ed1. Structures of the cephalopharyngeal skeleton are missing.

(Grossniklaus et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotypic analysis of different slp1 and slp2 alleles establishes an allelic series: slp1¹ < slp1^Δ41E < slp1^A509 < slp1³ < slp1^Δ46G < slp2^Δ66C < slp1^Δ34B = slp2^Δ34B.

(Grossniklaus et al., 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

slp1^A509

slp⁵⁰⁹

(Grossniklaus et al., 1992)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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