FB2026_02 , released June 18, 2026
Allele: Dmel\snfJA2
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General Information
Symbol
Dmel\snfJA2
Species
D. melanogaster
Name
FlyBase ID
FBal0039930
Feature type
allele
Associated gene
Dmel\snf
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Deshpande et al., 1996, Salz and Flickinger, 1996, Flickinger and Salz, 1994)
Mutagen
Delta2-3 transposase
(Flickinger and Salz, 1994)
Progenitor genotype
Df(1)PR110
(Flickinger and Salz, 1994)
Caused by aberration
Df(1)JA2
Cytology
Description

Deletion that removes the C-terminal end and extends into the adjacent gene, dhd.

(Salz and Flickinger, 1996)

Deletion that removes the P{lacW} insertion of Df(1)PR110 and also deletes 3kb of genomic DNA that removes the second exon of snf (including the carboxy-terminal RRM) and breaks in the intron.

(Flickinger and Salz, 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females (in the presence of the transgene P{dhd4.8}) are fertile. Heterozygotes with snfJ210 (in the presence of the transgene P{dhd4.8}) produce ovarian tumours.

      (Flickinger and Salz, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Female-lethal synergistic interaction with loss of function Sxl mutations (Sxlf1 and SxlfP7B0), SxlcF1.otu can suppress the interaction phenotype. One copy of P{SxlcF1} in wild type males, even under nonheat shock conditions, recovers only 2% of expected males. 15% of expected males are recovered from snfJA2; P{SxlcF1} males.

      (Salz and Flickinger, 1996)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      snfe8H and snf1 fail to complement each other and snfJA2 partially complements snfe8H and snf1.

      (Salz and Flickinger, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      snfJA2
      Name Synonyms
      Secondary FlyBase IDs
        References (3)