FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZChAT.7.4P
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General Information
Symbol
Ecol\lacZChAT.7.4P
Species
E. coli
Name
FlyBase ID
FBal0040976
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{ChAT.7.4kb-lacZ}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kitamoto et al., 1995, Kitamoto and Salvaterra, 1993, Kitamoto et al., 1992)
Progenitor genotype
Ecol\lacZC4.Adh
(Kitamoto et al., 1995)
Carried in construct
P{ChAT.7.4kb-lacZ}
Cytology
Description

7.4kb BamHI fragment containing ChAT 5' flanking region, transcription start site and 391bp of non coding sequence present in the first exon drives expression of Ecol\lacZC4.Adh.

(Kitamoto et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
ChAT_ChAT-7.4kb
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      accessory pharyngeal nerve
      (Kitamoto et al., 1995)
      cholinergic neuron
      (Kitamoto et al., 1995)
      supraesophageal ganglion
      (Kitamoto et al., 1995)
      sensory neuron of antenna
      (Kitamoto et al., 1992)
      leg sensillum | subset
      (Kitamoto et al., 1995)
      sensory neuron of adult labral sense organ
      (Kitamoto et al., 1995)
      sensory neuron of wing vein L1
      (Kitamoto et al., 1995)
      gnathal ganglion
      (Kitamoto et al., 1995)
      adult labral sense organ
      (Kitamoto et al., 1995)
      male terminalia sensillum | subset
      (Kitamoto et al., 1995)
      adult optic lobe
      (Kitamoto et al., 1992)
      wing vein L1 | restricted
      (Kitamoto et al., 1995)
      adult central complex
      (Kitamoto et al., 1992)
      sensory neuron of antennal sense organ
      (Kitamoto et al., 1995)
      antennal sense organ
      (Kitamoto et al., 1995)
      sensory neuron of male terminalia sensillum
      (Kitamoto et al., 1995)
      sensory neuron of leg sensillum
      (Kitamoto et al., 1995)
      adult ventral nerve cord
      (Kitamoto et al., 1995)
      adult labellum sensillum
      (Kitamoto et al., 1995)
      antenna
      (Kitamoto et al., 1992)
      adult hypocerebral ganglion
      (Kitamoto et al., 1995)
      sensory neuron of adult labellum sensillum
      (Kitamoto et al., 1995)
      sensory neuron of maxillary palp sense organ
      (Kitamoto et al., 1995)
      maxillary palp sense organ
      (Kitamoto et al., 1995)
      adult antennal lobe
      (Kitamoto et al., 1992)
      Additional Information
      Statement
      Reference

      In adult optic lobe, appears to be expressed in the same cells as Cha protein, but in the entire cell (including soma), whereas Cha protein is detected only at the nerve endings in the neuropil (thus expression appears to be more extensive).

      (Kitamoto et al., 1992)
       
      Marker for
      cholinergic neuron
      (Kitamoto et al., 1995)
      Reflects expression of
      ChAT
      (Kitamoto et al., 1995, Kitamoto et al., 1992)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZChAT.7.4P
      Ecol\lacZCha.7.4P
      lacZCha.7.4P
      Name Synonyms
      Secondary FlyBase IDs
        References (9)