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General Information
Symbol
Ecol\lacZsca-D120
Species
E. coli
Name
FlyBase ID
FBal0041046
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
D120
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion at coordinate -122 on the sca map, upstream of the transcription start site.

Insertion components
P{lacW}scaD120
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

The highest levels of Ecol\lacZ geneexpression are found in embryos, pupae, and third instar imaginal discs.In embryos, expression is first detected at 3 hrs of development and bygastrulation, is prominent in the neurogenic ectoderm. During germ bandextension, expression is seen in alternating domains of high and lowexpression along the anterior-posterior axis. By the early germ bandextended stage, expression is restricted to the neurogenic region. DuringCNS development, expression is higher in neuroblasts than in epidermalprecursor cells. Expression is later seen in regions of ectoderm that willgive rise to the PNS. In 3rd instar larvae, reporter gene expression isobserved in the optic lobes, the ventral nerve cord, and in scatteredcells in the imaginal discs. Expression in the eye disc (predominantly inphotoreceptor cell R8) and in the wing disc (in sensory bristleprecursors) was described in detail. Ectopic expression of Ecol\lacZ was seenin wing discs derived from homozygous acHw-49c or acHw-1 females.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ecol\lacZsca-D120
lacZsca-D120
Name Synonyms
Secondary FlyBase IDs
  • FBal0041932
References (6)