FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(var)3-7+t6.5
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General Information
Symbol
Dmel\Su(var)3-7+t6.5
Species
D. melanogaster
Name
FlyBase ID
FBal0042761
Feature type
allele
Associated gene
Dmel\Su(var)3-7
Associated Insertion(s)
Carried in Construct
P{RV-RV}
Also Known As
P{[ry+]Su(var)3-7 6.5kb}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Reuter et al., 1990)
wild_type
(Reuter et al., 1990)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Reuter et al., 1990)
wild_type
(Reuter et al., 1990)
Mutagen
in vitro construct
(Cleard et al., 1997, Reuter et al., 1990)
Progenitor genotype
Su(var)3-7+t10.4
(Reuter et al., 1990)
Carried in construct
P{RV-RV}
Cytology
Description

Contained within a 6.5kb genomic EcoRV fragment, internal to that of Su(var)3-7+t10.4.

(Reuter et al., 1990)
Allele components
Component
Use(s)
Regulatory region(s)
Su(var)3-7
Encoded product / tool
Su(var)3-7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:13,262,510..13,269,050 [+]
Linked to:
EcoRV-EcoRV restriction fragment
(Cleard et al., 1997, Reuter et al., 1990)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying Su(var)3-7+t6.5 show a decrease in crossing over between kni and pp.

      (Westphal and Reuter, 2002)

      Enchances the position effect variegation at the w locus caused by In(1)wm4 and Tp(3;Y)BL2 and seen in the insertion line P{hsp26-pt-T}39C-12, and enhances the position effect variegation at the y locus caused by Dp(1;f)1187, when expressed in a Su(var)3-7+ background. The suppression of variegation at the w locus caused by In(1)wm4 seen in Su(var)2055 flies is partly reduced if the flies are also carrying Su(var)3-7+t6.5.

      (Cleard et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies carrying three copies of Su(var)3-7+ (made using Su(var)3-7+t6.5) show variegation in w+ expression from the P{lacW}ciDplac insertion. Flies carrying three copies of Su(var)3-7+ (made using Su(var)3-7+t6.5) show variegation in w+ expression from the P{hsp26-pt-T}2-M010.R insertion. Flies carrying three copies of Su(var)3-7+ (made using Su(var)3-7+t6.5) show no variegation in w+ expression from the P{lacW}3-76a insertion. Flies carrying three copies of Su(var)3-7+ (made using Su(var)3-7+t6.5) show reduced w+ expression from the P{lacW}ciDplac insertion carried on either T(2;4)DB57A or T(2;4)DB47F compared to flies carrying two copies of Su(var)3-7+, but the w expression is uniform and is not variegated. Flies carrying three copies of Su(var)3-7+ (made using Su(var)3-7+t6.5) show enhanced variegation of w expression from the P{lacW}50C.x7 array.

      (Bushey and Locke, 2004)

      Rescues the enhancement of variegation of In(1)wm4.

      (Reuter et al., 1990)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Su(var)3-7+t6.5 rescues Su(var)3-7P9

      (Bushey and Locke, 2004)
      Partially rescues

      Su(var)3-7+t6.5 partially rescues Su(var)3-714

      (Seum et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(var)3-7+t6.5
      T21 A
      (Seum et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)