FlyBase Allele Report: Dmel\RabX1[k06908]

General Information

Symbol

Dmel\RabX1^k06908

Species

D. melanogaster

Name

FlyBase ID

FBal0042908

Feature type

allele

Associated gene

Dmel\RabX1

Associated Insertion(s)

P{lacW}mi^k06908

Carried in Construct

Also Known As

l(2)k06908

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Prokopenko et al., 2000, Spradling et al., 1999, FlyBase, 1996-, Kania et al., 1995, BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}mi^k06908

Cytology

Description

P{lacW} insertion approximately 294bp upstream of the 5' end of the chrw LD47384 cDNA.

(Prokopenko et al., 2000)

Insertion of a P{lacW} element.

(Kania et al., 1995)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:23,523,876..23,523,876 [+]

(Prokopenko et al., 2000, Spradling et al., 1999, FlyBase, 1996-, Kania et al., 1995, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, Kania et al., 1995)

Phenotype Manifest In

chordotonal organ | lateral

(Kania et al., 1995)

chordotonal organ | ventral

(Kania et al., 1995)

external sensory organ

(Kania et al., 1995)

multidendritic neuron

(Kania et al., 1995)

Detailed Description

Statement

Reference

Lethality occurs during pupal or adult stages. Homozygous embryos exhibit crowding and abnormal appearance of the lateral chordotonal (Lch) neurons. Ventral chordotonal organs, es and md neurons are also affected.

(Kania et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

4399

y¹ w^67c23; P{lacW}mi^k06908/CyO

Kyoto

102506

y¹ w^67c23 ; P{lacW}mi^k06908 / CyO

Notes on Origin

Discoverer

I. Kiss.

Comments

Complements: Dcp-1⁰²¹³². Complements: apt⁰⁶³⁶⁹.

(BDGP Project Members, 1994-1999)

Weak chrw allele. P{lacW} insertion can be excised and revert the lethal phenotype to wild type.

(Kania et al., 1995)

External Crossreferences and Linkouts ( 2 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

69/8

(Kania et al., 1995)

RabX1^k06908

chrw^k06908

(Christensen et al., 2008.12.28)

l(2)k06908

(Prokopenko et al., 2000, Spradling et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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