FB2026_03 , released September 17, 2026
Allele: Dmel\en::ftzEFEΔ34.hs
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General Information
Symbol
Dmel\en::ftzEFEΔ34.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0043030
Feature type
allele
Associated gene
en::ftz
Associated Insertion(s)
Carried in Construct
P{hs-EFEΔ34}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Smith and Jaynes, 1996, John et al., 1995)
Progenitor genotype
en::ftzEFE.hs
(Smith and Jaynes, 1996, John et al., 1995)
Carried in construct
P{hs-EFEΔ34}
Cytology
Description

Deletion of amino acids 169 to 399, en-derived regions 2, 3 and 4 (removes both the R domain and the most conserved portion of eh1).

(Smith and Jaynes, 1996)

An Hsp70 promoter drives expression of en in which the homeodomain (60 amino acids) has been replaced by the homeodomain of ftz, and in addition, codons 169-399 of en have been deleted (this removes a repression domain and a conserved motif).

(John et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
en::ftz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      After a 15 minute heat shock less than 10% embryos fail to hatch. Embryonic cuticle shows no ftz-dependent defects.

      (Tolkunova et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      en::ftzEFEΔ34.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (3)