FB2026_02 , released June 18, 2026
Allele: Dmel\feoS27
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General Information
Symbol
Dmel\feoS27
Species
D. melanogaster
Name
FlyBase ID
FBal0043277
Feature type
allele
Associated gene
Dmel\feo
Associated Insertion(s)
P{}feoS27
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
(Pokholkova et al., 1991, Pokholkova and Solov'eva, 1989)
Progenitor genotype
Associated Insertion(s)
P{}feoS27
Cytology
Description

Insertion of a P-element 37bp downstream of the ATG start codon.

(Verni et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      45.8% of cells in the brains of feoS27/Y third instar larvae are polyploid. The proportion of cells in anaphase in the mutant larval brains is normal (14.4% for the mutant larvae, compared to 15.0% for control larvae) and the mitotic index is 0.37 (compared to the wild-type value of 0.60). 73.7% of cells in the brains of feoS27/Df(1)v-L3 third instar larvae are polyploid. The proportion of cells in anaphase in the mutant larval brains is normal (11.9% for the mutant larvae, compared to 15.0% for control larvae) and the mitotic index is 0.30 (compared to the wild-type value of 0.60). Brains of feoS27/Y male larvae do not show defects in the early stages of neuroblast and ganglion mother cell divisions; the cells have regular asters and metaphase figures and they enter anaphase normally.

      (Verni et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      S27
      (Pokholkova and Solov'eva, 1989)
      feoS27
      l(1)9FeS27
      l(1)BP1S27
      (Pokholkova et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)