FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Mmp2k00604
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General Information
Symbol
Dmel\Mmp2k00604
Species
D. melanogaster
Name
FlyBase ID
FBal0043407
Feature type
allele
Associated gene
Dmel\Mmp2
Associated Insertion(s)
P{lacW}Mmp2k00604
Carried in Construct
Also Known As
l(2)k00604
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roch et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{lacW}Mmp2k00604
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      80.3% of Mmp2k00604 pupae show wing eversion defects 6 hours after puparium formation (eversion is complete at this time in wild-type animals); 45.5% have partially everted wings and 34.8% show a complete failure of disc eversion. 15.5% have leg eversion defects.

      The basement membrane of wing discs is not degraded in Mmp2k00604 pupae which fail to evert their wing discs.

      (Srivastava et al., 2007)

      Neuromuscular abnormalities are not observed in mutant larvae.

      (Meyer and Aberle, 2006)

      Lethality occurs during third instar larval or pupal stages. Mutants do not show any visible disc abnormalities.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      6/4
      (Roch et al., 1998)
      MMP2k00604
      (Matsubayashi et al., 2020)
      Mmp2k00604
      (Srivastava et al., 2007, Meyer and Aberle, 2006)
      l(2)02353k00604
      (BDGP Project Members, 1994-1999)
      l(2)k00604
      (Page-McCaw et al., 2003, Spradling et al., 1999)
      mmp2k00604
      (Kanda et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)