FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(2)gd13
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General Information
Symbol
Dmel\l(2)gd13
Species
D. melanogaster
Name
FlyBase ID
FBal0043605
Feature type
allele
Associated gene
Dmel\l(2)gd1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Agrawal et al., 1995)
Mutagen
ethyl methanesulfonate
(Agrawal et al., 1995)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during late larval and pupal stages. Hyperplasia of imaginal discs is not apparent as homozygous larvae or l(2)gd11/l(2)gd13 trans-heterozygous larvae and surviving pharate adults display a low frequency of hypertrophied and duplicated pattern (adult cuticular structures are apparently normal). Some pharate adults exhibited hypertrophies, outgrowths and ingrowths from the last tarsal segment of the legs, in some cases duplication of pattern elements in the wing and antennae. Clones in a Minute background show a loss of venation or abnormal thickening of veins. Occasionally clones have excessive folding of the wing margins and those located in the proximity of the anterior posterior compartment boundary realign the boundary. Clones also have a non-autonomous effect on surrounding wild type cells.

      (Agrawal et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      l(2)gd13 has wing | pharate adult stage phenotype, suppressible by vg1

      (Agrawal et al., 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Pharate adult wings of l(2)gd13 vg1 double mutants are partially restored compared to the single homozygotes. Clones in a vg1 homozygous background are recognisable by growths protuding from the wing blade, thus partially restoring the wing pattern by extensions of the wing blade areas (three-fold increase in wing blade area) and a span of clonal tissue in both dorsal and ventral wing surfaces.

      (Agrawal et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak allele.

      (Agrawal et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      l(2)gd13
      Name Synonyms
      Secondary FlyBase IDs
        References (1)