FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZci.2.2dis
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General Information
Symbol
Ecol\lacZci.2.2dis
Species
E. coli
Name
FlyBase ID
FBal0043955
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{2.2dis-ci+HS}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Schwartz et al., 1995)
Progenitor genotype
Carried in construct
P{2.2dis-ci+HS}
Cytology
Description

2.2dis element, located 2.5kb upstream from the start of transcription, is fused a non-heat-inducible fragment of the Hsp70 promoter fused to codon 8 of lacZ.

(Schwartz et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
ci_2.2dis
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      ventral midline of embryo
      (Schwartz et al., 1995)
      extended germ band stage
      organism | segmentally repeated
      (Schwartz et al., 1995)
      larval stage
      wing disc anterior compartment
      (Schwartz et al., 1995)
      Additional Information
      Statement
      Reference

      The 2.2 kb upstream fragment was sufficient, when coupled either with a Hsp70 promoter or a 1.2 kb ci promoter, to drive EcollacZ expression in embryos and imaginal discs in a wild-type ci expression pattern. EcollacZ expression is seen in a segmentally repeated pattern from embryonic gastrulation through germ band extension, and in the anterior compartment of imaginal discs.

      (Schwartz et al., 1995)
       
      Marker for
      Reflects expression of
      ci
      (Schwartz et al., 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZci.2.2dis
      lacZci.2.2dis
      Name Synonyms
      Secondary FlyBase IDs
        References (1)