FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dare1
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General Information
Symbol
Dmel\dare1
Species
D. melanogaster
Name
FlyBase ID
FBal0044544
Feature type
allele
Associated gene
Dmel\dare
Associated Insertion(s)
P{lacW}dare1
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Freeman and Carlson, 1996)
Progenitor genotype
Associated Insertion(s)
P{lacW}dare1
Cytology
Description

P{lacW} insertion 14bp downstream of the 5' end of the dare EST LD17269.

(Freeman et al., 1999)

Insertion of P-element within 10bp of the 5' end of the transcript.

(Freeman et al., 1997)

Insertion of a P{lacW} element 135 nucleotides 5' of a translational start site for a putative adrenodoxin reductase gene.

(Freeman and Carlson, 1996)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies show striking abnormalities in their avoidance response to the olfactory repellents 3-octanol, ethyl acetate and 4-methylcyclohexanol in an olfactory T maze; they show a severely reduced avoidance response. Flies have a normal electroantennogram amplitude in response to ethyl acetate. Neural degeneration is not seen in adult flies, even when aged 3-4 weeks.

      (Freeman et al., 1999)

      Mutant flies do not avoid high concentrations of odours to the same extent as wild type. In the case of ethyl acetate, mutant flies are attracted to concentrations which repel control flies. Mutants also show male-male courtship behaviour.

      (Freeman et al., 1997)

      Homozygotes fail to avoid high concentrations of 4-methylcyclohexanol, 3-octanol and benzaldehyde at the same levels as wild type.

      (Freeman and Carlson, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision of the P{lacW} element indicates that the dare1 olfactory defects result from the P{lacW} insertion.

      (Freeman et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ARGB335
      (Freeman and Carlson, 1996)
      dare1
      Name Synonyms
      Secondary FlyBase IDs
        References (10)