G18172309A
G1302A
W301term | hid-PA; W301term | hid-PB
W301term
TGG to TGA
Nucleotide substitution: G?A.
Amino acid replacement: W301term.
Mutant embryos show an increase in the number of dorsal, dorsolateral and lateral adult muscle precursor cells compared to wild type. The number of ventral adult muscle precursor cells is unaffected in these embryos.
Surviving transheterozygotes with Whid-A22 or Whid-A206 have an abnormal wing phenotype. The mutant wing appears opaque by comparison to wild type and occasionally contains trapped fluid. Transheterozygous males also possess improperly positioned terminalia. Some hemizygotes die before hatching and most of those that hatch possess properly formed cephalopharyngeal skeleton.
Mutant males can be ranked based on the severity of terminalia rotation: Df(3L)H99 > Whid-H109 > Whid-A22 > Whid-A206 > Whid-A329 > Whid-H89. The ranking is roughly similar to the one for the degree to which the alleles disrupt embryonic head development.