FlyBase Allele Report: Dmel\dally[ΔP-305]

General Information

Symbol

Dmel\dally^ΔP-305

Species

D. melanogaster

Name

FlyBase ID

FBal0045493

Feature type

allele

Associated gene

Dmel\dally

Associated Insertion(s)

P{?'PZ}dally^ΔP-305

Carried in Construct

Also Known As

dally³⁰⁵

Key Links

Allele class

loss of function allele

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

loss of function allele

(Nakato et al., 1995)

Mutagen

Delta2-3 transposase

(Nakato et al., 1995)

Progenitor genotype

dally^P1

(Nakato et al., 1995)

Associated Insertion(s)

P{?'PZ}dally^ΔP-305

Cytology

Description

Imprecise excision that removes genomic sequences adjacent to the site of insertion.

(Nakato et al., 1995)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal

(Nakato et al., 2002)

visible

(Nakato et al., 2002, Nakato et al., 1995)

Phenotype Manifest In

antenna

(Nakato et al., 2002)

eye

(Nakato et al., 1995)

female germline stem cell

(Guo and Wang, 2009)

genitalia

(Nakato et al., 2002, Nakato et al., 1995)

wing vein

(Nakato et al., 1995)

wing vein L5

(Nakato et al., 2002)

Detailed Description

Statement

Reference

The ovarioles of homozygous females show progressive loss of the germline stem cells (GSCs), with 56% of ovarioles containing no GSCs in the niche at day 10 after eclosion.

(Guo and Wang, 2009)

Homozygotes show 20% lethality. Homozygotes have a reduced antenna, incomplete wing vein 5 and reduced genitalia, with incomplete penetrance.

(Nakato et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

dally^ΔP-305 has partially lethal phenotype, non-enhanceable by Df(2R)59AB/+

(Nakato et al., 2002)

Suppressed by

Statement

Reference

dally^ΔP-305 has partially lethal phenotype, suppressible by CycA³/CycA[+]

(Nakato et al., 2002)

NOT suppressed by

Statement

Reference

dally^ΔP-305 has partially lethal phenotype, non-suppressible by Df(2R)59AB/+

(Nakato et al., 2002)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

dally^ΔP-305 has antenna phenotype, non-enhanceable by Df(2R)59AB/+

(Nakato et al., 2002)

dally^ΔP-305 has genitalia phenotype, non-enhanceable by Df(2R)59AB/+

(Nakato et al., 2002)

dally^ΔP-305 has wing vein L5 phenotype, non-enhanceable by Df(2R)59AB/+

(Nakato et al., 2002)

NOT suppressed by

Statement

Reference

dally^ΔP-305 has antenna phenotype, non-suppressible by Df(2R)59AB/+

(Nakato et al., 2002)

dally^ΔP-305 has genitalia phenotype, non-suppressible by Df(2R)59AB/+

(Nakato et al., 2002)

dally^ΔP-305 has wing vein L5 phenotype, non-suppressible by Df(2R)59AB/+

(Nakato et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The lethality seen in dally^ΔP-305 homozygotes is reduced if they are also heterozygous for CycA³.

(Nakato et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dally³⁰⁵

(Xia et al., 2012, Guo and Wang, 2009)

dally^ΔP-305

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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