FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fj2
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General Information
Symbol
Dmel\fj2
Species
D. melanogaster
Name
FlyBase ID
FBal0045636
Feature type
allele
Associated gene
Dmel\fj
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Villano and Katz, 1995)
Mutagen
Delta2-3 transposase
(Villano and Katz, 1995)
Progenitor genotype
fj9-II
(Villano and Katz, 1995)
Cytology
Description

Excision of the P{lacW} insertion and deletion of adjacent genomic DNA.

(Villano and Katz, 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes show fusion of tarsal segments 2 and 3.

      (Buckles et al., 2001)

      Homozygotes exhibit loss of growth in the proximal distal axis of the leg and wing. The middle tarsal segments, T2 and T3, are replaced by a single segment that appears to be a fusion of the two. The T1 tarsal segment, the tibia and femur are truncated. Leg phenotype arises from an initial failure in the proliferation of a subset of tarsal segments as well as failure to initiate the T2/T3 segment boundary. The intervein distance is significantly reduced due to a shortened separation between the anterior and posterior crossveins, a reduction in the total number of cells in this region. The external eye shows occasional disordered lens facets and a small number of ommatidia appear fused.

      (Villano and Katz, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      fj2 has visible phenotype, enhanceable by Df(3L)st-j7

      (Buckles et al., 2001)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      fj2 has leg joint phenotype, enhanceable by Df(3L)st-j7

      (Buckles et al., 2001)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      fj2/fj2 ; Df(3L)st-j7/+ flies show partial or complete fusions of tarsal segment 1 and 2 as well as the fusion of tarsal segments 2 and 3 seen in fj2 single mutants.

      (Buckles et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fj2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)