FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hepr45
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General Information
Symbol
Dmel\hepr45
Species
D. melanogaster
Name
FlyBase ID
FBal0045850
Feature type
allele
Associated gene
Dmel\hep
Associated Insertion(s)
P{?SDFL}hepr45
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Glise et al., 1995)
Mutagen
PM hybrid dysgenesis
(Glise et al., 1995)
Progenitor genotype
hep1
(Glise et al., 1995)
Associated Insertion(s)
P{?SDFL}hepr45
Cytology
Description

Imprecise excision of the P-element insertion.

(Glise et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      hepr45 has lethal phenotype, non-suppressible by Mmus\Map2k7Ubi-p63E.PH

      (Holland et al., 1997)

      hepr45 has lethal phenotype, non-suppressible by Xlae\map2k4.LUbi-p63E.PH

      (Holland et al., 1997)

      hepr45 has lethal phenotype, non-suppressible by Mmmm\Sek1Ubi-p63E.PH

      (Holland et al., 1997)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The lethality of hemizygous males is not significantly rescued by Mmus\Prkmk7Ubi-p63E.PH, Xlae\Mek2Ubi-p63E.PH or Mmmm\Sek1Ubi-p63E.PH.

      (Holland et al., 1997)
      Complementation and Rescue Data
      Rescued by

      hepr45 is rescued by hepUbi-p63E.PG

      (Holland et al., 1997)
      Comments

      The lethality of hemizygous males is rescued by hepUbi-p63E.PG, giving rise to viable, fertile adults in 55% of cases.

      (Holland et al., 1997)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hepr45
      Name Synonyms
      Secondary FlyBase IDs
        References (2)