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General Information
Symbol
Dmel\l(3)mbtE2
Species
D. melanogaster
Name
FlyBase ID
FBal0046090
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G27267641A

Amino acid change:

W1099term | l(3)mbt-PB

Reported amino acid change:

W1099term

Comment:

G to A nucleotide change at the second or third position of the wild type Trp codon leads to a nonsense mutation (exact site of mutation unspecified). The mutation was annotated at the second base of the codon.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: W1099term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference

l(3)mbtE2/l(3)mbt[+] is a non-enhancer of visible phenotype of CycEJP

NOT Suppressor of
Statement
Reference

l(3)mbtE2/l(3)mbt[+] is a non-suppressor of visible phenotype of CycEJP

Phenotype Manifest In
NOT Enhancer of
Statement
Reference

l(3)mbtE2/l(3)mbt[+] is a non-enhancer of eye phenotype of CycEJP

NOT Suppressor of
Statement
Reference

l(3)mbtE2/l(3)mbt[+] is a non-suppressor of eye phenotype of CycEJP

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

In trans Df(3R)D605 or Df(3R)mbtPE3, l(3)mbt alleles form the following phenotypic series: l(3)mbtGM161 < l(3)mbtts1 < l(3)mbtGM79 < l(3)mbtE2 < l(3)mbtGM76. Phenotypes range from weak maternal-effect mitotic asynchrony to a severe mitotic block to oogenesis defects in trans-heterozygous females. Each of these phenotypes is temperature sensitive: phenotypes increase in severity as the temperature is raised from 18 to 29oC.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)