FlyBase Allele Report: Dmel\pk[pk-sple-26]

General Information

Symbol

Dmel\pk^pk-sple-26

Species

D. melanogaster

Name

FlyBase ID

FBal0046284

Feature type

allele

Associated gene

Dmel\pk

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Gubb et al., 1999)

Progenitor genotype

In(2LR)O

(Gubb et al., 1999)

Caused by aberration

Tp(2;2)pk-sple²⁶

Cytology

Description

Lesion present between 50.3 and 53.5kb downstream of zero (zero being 973bp proximal to the pk transcription start site.).

(Gubb et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Gubb et al., 1999)

visible | recessive

(Gubb, 1998.2.25)

Phenotype Manifest In

abdomen

(Gubb et al., 1999)

eye

(Gubb et al., 1999)

leg

(Gubb et al., 1999)

scutum

(Gubb et al., 1999)

wing

(Gubb et al., 1999)

Detailed Description

Statement

Reference

Causes no embryonic phenotype even when homozygous mutant embryos develop from homozygous mutant mothers. Has a weak polarity phenotype in the wing, notum, abdomen, eye and legs. Denticle belt morphology and denticle orientation remains wild-type.

(Gubb et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

pk^pk-sple-26 is an enhancer of abnormal cell polarity phenotype of Scer\GAL4^hs.2sev, Vang^UAS.cWa

(Jenny et al., 2003)

Phenotype Manifest In

Enhancer of

Statement

Reference

pk^pk-sple-26 is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, Vang^UAS.cWa

(Jenny et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (5)

Bloomington

8889

Df(2R)sple-D1, Adc^b-1 cn¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26

44232

pk^sple-4 cn¹ bw¹ speck¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26

4130

In(2R)DX8, Dscam1¹⁷ cn¹ bw¹ speck¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26

4118

Tp(2;3)DX11, l(2)43Bb³ cn¹ bw¹ speck¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26

Kyoto

107597

In(2R)DX8, Dscam1¹⁷ cn¹ bw¹ speck¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26

Notes on Origin

Discoverer

D. Coulson.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

pk-sple²⁶

(Jenny et al., 2003, Roote, 1996.3.6)

pk-sple^81h

(Roote, 1996.3.6)

pk²⁶

pk^pk-sple-26

sple²⁶

Name Synonyms

Secondary FlyBase IDs

FBal0046519

References (6)

Report Sections

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