FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\poloDD1
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General Information
Symbol
Dmel\poloDD1
Species
D. melanogaster
Name
FlyBase ID
FBal0046287
Feature type
allele
Associated gene
Dmel\polo
Associated Insertion(s)
Carried in Construct
Also Known As
polo3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(White-Cooper, 1996.4.29, White-Cooper et al., 1996)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eggs derived from polo1/poloDD1 females complete meiosis and show a phenotype similar to that of eggs derived from polo1 females; they contain many bipolar anastral spindles but lack structures containing polar bodies.

      (Riparbelli et al., 2000)

      polo1/poloDD1 males show defects in spermatogenesis.

      (Carmena et al., 1998)

      Transheterozygotes are female sterile, exhibit no cuticular, testis or premeiotic defects but do exhibit a mutant brain phenotype. No defects in spermatogenesis so transheterozygous males are fertile.

      (White-Cooper et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Phenotype assayed in trans with a multiple mutant chromosome carrying mutations of polo, mgr, asp, stg and gnu.

      (White-Cooper et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      polo3
      (Riparbelli et al., 2000, Carmena et al., 1998, White-Cooper et al., 1996)
      poloDD1
      Name Synonyms
      Secondary FlyBase IDs
        References (4)