FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sliF119
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General Information
Symbol
Dmel\sliF119
Species
D. melanogaster
Name
FlyBase ID
FBal0046486
Feature type
allele
Associated gene
Dmel\sli
Associated Insertion(s)
P{lacW}sliF119
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Battye et al., 2001)
Mutagen
P-element activity
(Rothberg et al., 1990)
Progenitor genotype
Associated Insertion(s)
P{lacW}sliF119
Cytology
Description

Insertion of P{lacW} 10bp upstream of the coding region and transcription initiation sequence.

(Rothberg et al., 1990)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      17% of expected mutant embryos hatch as first instar larvae. The latest observed stage of mutants is adult. Nerve cord length is 80% of embryo length. Midline guidance failure of repellence phenotype, evidenced by midline crossing, is mild. Shows midline deviations in the most medial longitudinal fascicle but retains a relatively intact lateral fascicle.

      (Battye et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      sliF119 has larval ventral nerve cord phenotype, enhanceable by robo[+]/robo11

      (Battye et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Percentage of segments with midline crossovers in robo1/sliF119 transheterozygotes is 37%.

      (Battye et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      sliF81 and sliF119 are probably the result of the same insertion event.

      (Rothberg et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sliF119
      slitF119
      (Battye et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)