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General Information
Symbol
Dmel\spen16T1
Species
D. melanogaster
Name
FlyBase ID
FBal0048683
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Clonal analysis reveals that spen is required for eye development. Homozygous ommatidia lack either R7 or one of more other photoreceptors. Embryos derived from homozygous germline clones show no indication of absent or abnormal tor pathway signalling.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

spen16T1 is an enhancer of eye phenotype of Raf::tor12D.sev

Additional Comments
Genetic Interactions
Statement
Reference

Dominantly enhances the rough eye phenotype of phl::tor12D.sev. Modifies the eye phenotype of phl12. Enhances phl12 phenotype resulting in synthetic lethality.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Alleles of spen exhibit complex complementation relationships. spen14O1 and spen16H1 partially complement, as do spen14O1 and spen16T1. spen16H1 completely fails to complement spen16T1.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)