Mutation causes organelle-filled axonal swellings that exhibit abnormal accumulation of nerve terminal proteins, including syt.
Khc6/KhcBD heteroallelic flies cultured at 22oC become paralysed at 39oC. The temperature threshold for this behavior is higher than that for mlenap-ts1 or parats1, and the timecourse of recovery is slower. For many minutes the flies remain sluggish. Shows no bang sensitivity.