FlyBase Allele Report: Dmel\hth[dtl-J186]

General Information

Symbol

Dmel\hth^dtl-J186

Species

D. melanogaster

Name

FlyBase ID

FBal0049449

Feature type

allele

Associated gene

Dmel\hth

Associated Insertion(s)

Carried in Construct

Also Known As

hth^J186

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Kurant et al., 1998)

Mutagen

ethyl methanesulfonate

(Kurant et al., 1998, Pai et al., 1998, Salzberg et al., 1994)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Salzberg et al., 1994)

lethal - all die during embryonic stage | recessive

(Kurant et al., 1998)

some die during embryonic stage | recessive

(Kurant et al., 1998)

Phenotype Manifest In

abdominal 1 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 2 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 3 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 4 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 5 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 6 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

abdominal 7 lateral pentascolopidial chordotonal organ lch5

(Salzberg et al., 1994)

larval abdominal 1 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 2 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 3 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 4 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 5 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 6 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal 7 lch5 neuron | embryonic stage

(Kurant et al., 1998)

larval abdominal lch5 neuron

(Kurant et al., 2001)

Detailed Description

Statement

Reference

Mutant embryos show a relatively mild phenotype in the PNS, which consists mainly of dorsal localisation of LCh5 neurons in some of the abdominal segments.

(Kurant et al., 2001)

The LCh5 neurons are located in a more dorsal position than normal in 36% of the abdominal segments in homozygous embryos.

(Kurant et al., 1998)

Defect in embryonic PNS development: abnormal position of LCh5 organs, possibly due to neuronal migration.

(Salzberg et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

J186

(Pai et al., 1998)

dtl^J186

hth^J186

(Kurant et al., 2001, Kurant et al., 1998)

hth^dtl-J186

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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