FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Irbp+t8.8
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General Information
Symbol
Dmel\Irbp+t8.8
Species
D. melanogaster
Name
FlyBase ID
FBal0050168
Feature type
allele
Associated gene
Dmel\Irbp
Associated Insertion(s)
Carried in Construct
P{gIRBP8.8}
Also Known As
gDmKu70
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Beall and Rio, 1996)
wild_type
(Beall and Rio, 1996)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Beall and Rio, 1996)
wild_type
(Beall and Rio, 1996)
Mutagen
in vitro construct
(Beall and Rio, 1996)
Progenitor genotype
Carried in construct
P{gIRBP8.8}
Cytology
Description

8.8kb BamHI fragment encompassing the Irbp gene.

(Beall and Rio, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Irbp
Encoded product / tool
Irbp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:11,408,186..11,416,543 [+]
Linked to:
BamHI-BamHI restriction fragment
Comment:

Position of rescue fragment on reference sequence inferred by FlyBase curator.

(Beall and Rio, 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Irbp+t8.8 is a suppressor | partially of abnormal neuroanatomy phenotype of Hsap\HTT103Q.Ex1.UAS, Scer\GAL4GMR.long

      (Tamura et al., 2011)

      Irbp+t8.8 is a suppressor of female sterile phenotype of BlmD3/BlmD2

      (Beall and Rio, 1996)

      Irbp+t8.8 is a suppressor of chemical sensitive phenotype of BlmD3/BlmD2

      (Beall and Rio, 1996)
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Rescues the female sterility and MMS sensitivity of mus309 mutants.

      (Beall and Rio, 1996)
      Xenogenetic Interactions
      Statement
      Reference

      Irbp+t8.8 partially suppresses the photoreceptor degeneration seen in flies expressing Hsap\HTT103Q.Ex1.Scer\UAS under the control of Scer\GAL4GMR.long.

      (Tamura et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Irbp+t8.8
      mus309+t8.8
      Name Synonyms
      Secondary FlyBase IDs
        References (3)