FlyBase Allele Report: Dmel\Blm[D2]

General Information

Symbol

Dmel\Blm^D2

Species

D. melanogaster

Name

FlyBase ID

FBal0012662

Feature type

allele

Associated gene

Dmel\Blm

Associated Insertion(s)

Carried in Construct

Also Known As

mus309^d2

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Boyd et al., 1981)

Progenitor genotype

Cytology

Description

FlyBase curator comment: This is a TGG to TAG mutation.

(Dushay, 2013.12.6)

Nucleotide substitution: G?A.

(Dushay, 2013.12.6)

Amino acid replacement: W922term.

(Dushay, 2013.12.6, Kusano et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:11,738,780..11,738,780 [-]

Nucleotide change:

G11738780A

Reported nucleotide change:

G?A

Amino acid change:

W922term | Blm-PA

Reported amino acid change:

W922term

Comment:

Nonsense mutation (TGG to TAG) at Trp codon.

(Dushay, 2013.12.6, Kusano et al., 2001)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of Bloom syndrome

CEA

(McVey et al., 2007, Johnson-Schlitz and Engels, 2006, Kusano et al., 2001)

CEA with Blm^D3

(McVey et al., 2004)

CEA with Blm^N1

(Lafave et al., 2014)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal DNA repair

(Beall and Rio, 1996)

abnormal DNA repair (with Blm^N1)

(Kuo et al., 2014)

abnormal mitotic cell cycle (with Blm^N1)

(Kuo et al., 2014)

chemical sensitive (with Blm^D3)

(Beall and Rio, 1996)

chemical sensitive (with Blm^N1)

(Kuo et al., 2014)

chemical sensitive (with Df(3R)T-7)

(Kusano et al., 2001)

chemical sensitive | recessive

(Kooistra et al., 1999)

chemical sensitive | semidominant

(Boyd et al., 1981)

female sterile (with Blm^D3)

(Beall and Rio, 1996)

female sterile (with Df(3R)T-7)

(Kusano et al., 2001)

female sterile | recessive

(Szabad, 1998.4.8)

lethal - all die during embryonic stage | maternal effect (with Blm^D3)

(McVey et al., 2007)

lethal - all die during embryonic stage | maternal effect (with Blm^N1)

(McVey et al., 2007)

male semi-sterile (with Df(3R)T-7)

(Kusano et al., 2001)

male semi-sterile | dominant

(Kusano et al., 2001)

partially lethal (with Blm^D3)

(Portin, 2005)

radiation sensitive (with Blm^D3)

(McVey et al., 2007)

radiation sensitive (with Blm^N1)

(Kuo et al., 2014)

radiation sensitive | recessive

(Kooistra et al., 1999)

some die during embryonic stage | maternal effect (with Blm^D3)

(McVey et al., 2007)

some die during embryonic stage | maternal effect (with Blm^N1)

(McVey et al., 2007)

viable

(Johnson-Schlitz and Engels, 2006)

Phenotype Manifest In

Detailed Description

Statement

Reference

Blm^N1/Blm^D2 animals are hyper-sensitive to the cross-linking agent HN2, the mono-adduct generator MMS, and ionizing radiation.

Spontaneous mitotic crossovers are elevated in Blm^N1/Blm^D2 males.

Blm^N1/Blm^D2 animals show a severely decreased ability to complete 'synthesis-dependent strand annealing' repair of a DNA gap.

(Kuo et al., 2014)

No significant change in single-strand annealing frequency between mus309^D2/mus309^D3 mutant flies and controls when the sequence in question has 100% sequence identity (MtnB^{2x259gen.Scer\SceI.RS.T:Avic\GFP-EGFP}). A small increase in single stranded annealing is observed during the repair of a construct with a 1-bp mismatch in mutant flies (MtnB^{mutgen.Scer\SceI.RS.T:Avic\GFP-EGFP}). With a more divergent construct (MtnB^{cDNA-gen.Scer\SceI.RS.T:Avic\GFP-EGFP} a strong increase in single stranded annealing frequency is detected in mus309^D2/mus309^D3 mutants.

Suppression of homologous single stranded annealing (SSA) is relaxed in mus309^D2/mus309^D3 mutants, resulting in a 4.5-fold elevation in SSA frequencies. Discontinuous repair patterns are never seen in these mutants.

(Kappeler et al., 2008)

Embryos derived from mus309^D2/mus309^D3 and mus309^N1/mus309^D2 females have an extremely low hatch rate.

Only 40% of the embryos derived from mus309^N1/mus309^D2 females have cellularised by 4-6 hours after egg laying, and none have gastrulated by this time (in contrast to embryos derived from wild-type females where 99% have cellularised and 96% have gastrulated by this time).

mus309^N2/mus309^D2 females show an increased rate of X chromosome meiotic nondisjunction compared to wild-type females.

mus309^D2/mus309^D3 larvae are hypersensitive to gamma radiation, showing reduced survival to adulthood after irradiation with doses of radiation that do not have a large effect on the survival of wild-type larvae.

Studies of excision and repair events of P{hsw^a} in mus309^N1/mus309^D2, mus309^N2/mus309^D2 and mus309^D2/mus309^D3 males indicate that synthesis-dependent strand annealing (SDSA) is severely compromised in these animals.

mus309^N1/mus309^D2, mus309^N2/mus309^D2 and mus309^D2/mus309^D3 males show elevated rates of mitotic crossing over compared to control males.

(McVey et al., 2007)

mus309^D2/mus309^D3 mutants have a similar frequency of single-strand annealing repair (SSA) compared to controls in a P{wIw.FRT} hemizygous assay to study DNA double-stranded break repair when assayed at 32^oC or 38^oC.

(Wei and Rong, 2007)

Homozygotes of mus309^D2 are viable.

Compared with wild-type flies, mus309^D2/Df(3R)T-7 flies display altered measurements of parameters related to double-strand break repair.

(Johnson-Schlitz and Engels, 2006)

Blm^D2/Blm^D3 flies are semilethal.

(Portin, 2005)

The complete copia element in w^a.hs has an LTR at each end. Following excision of P{hsw^a}, repair by SDSA (synthesis-dependent strand annealing) can lead to excision of this copia element due to annealing at these LTRs, resulting in red eyed progeny. Incomplete SDSA, where joining has occurred independently of annealing of homologous ends, can delete parts of the w ORF in w^a.hs resulting in yellow eyed progeny. The frequency of red eyed progeny following excision of P{hsw^a}sd^wa using H{PΔ2-3}HoP2.1 (and therefore of complete SDSA) is decreased from 6% to 0.2% in a mus309^D2/mus309^D3 background, but the frequency of yellow eyed progeny (and therefore of incomplete SDSA) is increased from 10% to 15.5%. This background also increases the proportion of hemizygous lethal sd deletions resulting from this excision event (from 2.4% to 25%), and the proportion of non-lethal sd deletions from 7% to 35.5%.

(McVey et al., 2004)

mus309^D2/Df(3R)T-7 animals are sensitive to methyl methanesulfonate. Chromosome nondisjunction and chromosome loss is increased more than tenfold in mus309^D2/Df(3R)T-7 males relative to wild type and heterozygous controls. An elevated frequency of sperm which have lost one of two dominant markers on opposite ends of the Y chromosome is also seen.

(Kusano et al., 2001)

mus309^D2/mus309^D3 animals show no defects in a DNA damage checkpoint assay.

(Brodsky et al., 2000)

mus309^D2/mus309^D3 mutants are threefold more sensitive to X rays than wild-type flies.

(Kooistra et al., 1999)

Unable to repair double-strand DNA breaks. Hypersensitive to methyl methanesulfonate (MMS).

(Beall and Rio, 1996)

Hypersensitive to methyl methanesulfonate. Sensitive to 0.008% HN2.

(Boyd et al., 1981)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Blm^N1/Blm^D2 has abnormal DNA repair phenotype, enhanceable by Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^N1/Blm^D2 has chemical sensitive phenotype, enhanceable by Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^N1/Blm^D2 has radiation sensitive phenotype, enhanceable by Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^D3/Blm^D2 has radiation sensitive phenotype, enhanceable by okr^A19-10/okr^17-11

(Kooistra et al., 1999)

Suppressed by

Statement

Reference

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103 has lethal | first instar larval stage phenotype, suppressible by spn-A^unspecified

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus81^Nhe has lethal phenotype, suppressible by spn-A^093A/spn-A^093A

(Trowbridge et al., 2007)

Df(3R)T-7/Blm^D2 has chemical sensitive phenotype, suppressible by Hsap\XRCC6^hs.PB

(Kusano et al., 2001)

Blm^D3/Blm^D2 has chemical sensitive phenotype, suppressible by Irbp^+t8.8

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has female sterile phenotype, suppressible by Irbp^+t13

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has chemical sensitive phenotype, suppressible by Irbp^+t13

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has female sterile phenotype, suppressible by Irbp^+t8.8

(Beall and Rio, 1996)

NOT suppressed by

Statement

Reference

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has lethal | pupal stage phenotype, non-suppressible by spn-A^unspecified

(Andersen et al., 2011)

Blm^D3/Blm^D2 has female sterile phenotype, non-suppressible by Irbp^6.8

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has chemical sensitive phenotype, non-suppressible by Irbp^6.8

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has female sterile phenotype, non-suppressible by Irbp^Δ

(Beall and Rio, 1996)

Blm^D3/Blm^D2 has chemical sensitive phenotype, non-suppressible by Irbp^Δ

(Beall and Rio, 1996)

Enhancer of

Statement

Reference

Blm^N1/Blm^D2 is an enhancer of abnormal DNA repair phenotype of Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^N1/Blm^D2 is an enhancer of chemical sensitive phenotype of Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^N1/Blm^D2 is an enhancer of radiation sensitive phenotype of Fancm⁰⁶⁹³/Df(3R)ED6058

(Kuo et al., 2014)

Blm^D3/Blm^D2 is an enhancer of radiation sensitive phenotype of okr^A19-10/okr^17-11

(Kooistra et al., 1999)

Suppressor of

Statement

Reference

mus309[+]/Blm^D2 is a suppressor of visible phenotype of Caf1-180^UAS.cSa, Scer\GAL4^ey.PH

(Song et al., 2007)

mus309[+]/Blm^D2 is a suppressor of increased cell death phenotype of Caf1-180^UAS.cSa, Scer\GAL4^ey.PH

(Song et al., 2007)

Blm^D2 is a suppressor of viable phenotype of mus81^5.1

(Johnson-Schlitz and Engels, 2006)

Other

Statement

Reference

Blm^N1/Blm^D2, Fancm⁰⁶⁹³/Df(3R)ED6058 has viable phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, Gen^Z5997, spn-A^093A/spn-A³ has lethal - all die during pupal stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mus81^Nhe, spn-A^093A/spn-A³ has partially lethal - majority live phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mei-9^a has viable phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mus81^Nhe has lethal - all die during pharate adult stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has lethal - all die during pupal stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973, spn-A^093A/spn-A³ has lethal - all die during pupal stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, slx1^F93I has lethal - all die during pupal stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, Gen^Z5997 has lethal - all die during first instar larval stage phenotype

(Kuo et al., 2014)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has lethal | pupal stage phenotype

(Andersen et al., 2011, Andersen et al., 2009)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103, spn-A^unspecified has lethal | pupal stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus81^Nhe has lethal | pharate adult stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, slx1^F93I has lethal | pupal stage phenotype

(Andersen et al., 2011)

Blm^N2/Blm^D2, Gen^unspecified/Df(3L)Exel6103 has lethal | pharate adult stage phenotype

(Andersen et al., 2011)

Blm^N2/Blm^D2, mus312^D1/mus312^Z1973 has lethal | pupal stage phenotype

(Andersen et al., 2011)

Blm^N2/Blm^D2, mus81^Nhe has viable phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Df(3R)HKK1, Dp(3;3)HKK2 has lethal | pupal stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103 has lethal | first instar larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has melanotic mass phenotype | third instar larval stage phenotype

(Andersen et al., 2009)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973, spn-A^093A/spn-A³ has lethal | pupal stage phenotype

(Andersen et al., 2009)

Blm^N1/Blm^D2, mei-9^unspecified has viable phenotype

(Andersen et al., 2009)

Blm^D3/Blm^D2, mus81^Nhe has lethal phenotype

(Trowbridge et al., 2007)

Blm^N1/Blm^D2, mus81^Nhe has lethal phenotype

(Trowbridge et al., 2007)

Blm^N1/Blm^D2, mms4^ex1 has lethal phenotype

(Trowbridge et al., 2007)

Blm^D2, mus81^5.1, spn-A¹ has viable phenotype

(Johnson-Schlitz and Engels, 2006)

Phenotype Manifest In

Suppressed by

Statement

Reference

Blm^N1/Blm^D2, mus81^Nhe has condensed chromosome phenotype, suppressible by spn-A^unspecified

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has condensed chromosome phenotype, suppressible by spn-A^unspecified

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has salivary gland imaginal ring phenotype, suppressible by spn-A^unspecified

(Andersen et al., 2011)

NOT suppressed by

Statement

Reference

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has larval brain phenotype, non-suppressible by spn-A^unspecified

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has imaginal disc | larval stage phenotype, non-suppressible by spn-A^unspecified

(Andersen et al., 2011)

Suppressor of

Statement

Reference

mus309[+]/Blm^D2 is a suppressor of eye phenotype of Caf1-180^UAS.cSa, Scer\GAL4^ey.PH

(Song et al., 2007)

Other

Statement

Reference

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has larval brain phenotype

(Andersen et al., 2011, Andersen et al., 2009)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103, spn-A^unspecified has larval brain phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103, spn-A^unspecified has salivary gland imaginal ring phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103, spn-A^unspecified has imaginal disc | larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Gen^unspecified/Df(3L)Exel6103, spn-A^unspecified has condensed chromosome phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus81^Nhe has condensed chromosome phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has salivary gland imaginal ring phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has imaginal disc | larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has condensed chromosome phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, slx1^F93I has imaginal disc | larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, slx1^F93I has larval neuroblast | larval stage phenotype

(Andersen et al., 2011)

Blm^N2/Blm^D2, Gen^unspecified/Df(3L)Exel6103 has imaginal disc | larval stage phenotype

(Andersen et al., 2011)

Blm^N2/Blm^D2, Gen^unspecified/Df(3L)Exel6103 has condensed chromosome phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Df(3R)HKK1, Dp(3;3)HKK2 has imaginal disc | larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, Df(3R)HKK1, Dp(3;3)HKK2 has larval neuroblast | larval stage phenotype

(Andersen et al., 2011)

Blm^N1/Blm^D2, mus312^D1/mus312^Z1973 has imaginal disc | third instar larval stage phenotype

(Andersen et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

A very small proportion of Pol32^L30/Pol32^L27 adults show an etched abdomen phenotype; this phenotype is not much affected in a Blm^D2/+ background.

(Ji et al., 2019)

The rate of spontaneous mitotic crossovers in Blm^N1/Blm^D2 Fancm⁰⁶⁹³/Df(3R)ED6058 males is not significantly different from that in Fancm⁰⁶⁹³/Df(3R)ED6058 males, but is significantly lower than in Blm^N1/Blm^D2 males.

(Kuo et al., 2014)

mus309^N1/mus309^D2 slx1^F93I and mus309^N1/mus309^D2 Df(3R)HKK1, Dp(3;3)HKK2 double mutant animals die as early pupae, larvae lack imaginal discs and larval neuroblasts are frequently polyploid.

mus309^N1/mus309^D2 mus312^D1/mus312^Z1973 double mutant larvae have small brains, lack imaginal discs and have a reduced number of salivary gland imaginal ring cells. The nuclei of the remaining salivary gland imaginal ring cells appear larger than normal. Mitotic neuroblasts in these larvae show extreme genome instability; no mitotic nuclei with completely intact chromosomes are detected and approximately one-third show polyploidy.

Mitotic neuroblasts in mus81^Nhe ; mus309^N1/mus309^D2 double mutant larvae show an increased frequency of broken chromosomes compared to wild type.

The addition of spn-A^unspecified significantly decreases the number of chromosome breaks seen in mitotic neuroblasts of mus81^Nhe ; mus309^N1/mus309^D2 larvae.

Gen^unspecified/Df(3L)Exel6103 mus309^N1/mus309^D2 spn-A^unspecified triple mutant larvae have small brain and generally lack imaginal discs (although very small rudimentary discs are occasionally visible). Salivary gland imaginal ring cells are reduced in number and have enlarged nuclei. Mitotic neuroblasts have numerous chromosome breaks.

The addition of spn-A^unspecified suppresses the the chromosome breakage and polyploidy phenotypes seen in mitotic neuroblasts of mus309^N1/mus309^D2 mus312^D1/mus312^Z1973 larvae, and also suppresses the defects in the salivary gland imaginal ring cells seen in the mus309^N1/mus309^D2 mus312^D1/mus312^Z1973 double mutants. However, addition of spn-A^unspecified does not suppress the pupal lethality, small brains and lack of imaginal discs seen in the mus309^N1/mus309^D2 mus312^D1/mus312^Z1973 double mutants.

Mitotic neuroblasts in Gen^unspecified/Df(3L)Exel6103 mus309^D2/mus309^N2 double mutant larvae show an increased frequency of broken chromosomes compared to wild type.

mus309^D2/mus309^N2 mus312^D1/mus312^Z1973 double mutant larvae generally lack imaginal discs (although small, severely underdeveloped discs are sometimes seen in third instar larvae).

(Andersen et al., 2011)

mus312^D1/mus312^Z1973, mus309^D2/mus309^N1 double mutants are inviable, dying after pupariation. Third-instar larvae have melanotic tumors and lack larval imaginal discs. Larval brains of double mutants are greatly reduced in size.

The spn-A³/spn-A^093A transheterozygous condition does not suppress the lethality of mus312^D1/mus312^Z1973, mus309^D2/mus309^N1 double mutants.

(Andersen et al., 2009)

The small-eye phenotype of flies expressing Caf1-180^Scer\UAS.cSa under the control of Scer\GAL4^ey.PH is suppressed by heterozygous Blm^D2.

(Song et al., 2007)

The double mutant of mus81^5.1 and mus309^D2 is lethal, even though both mutations are viable individually. Most of the double mutants survive until the late larval stages, but die during pupation.

The triple mutant of mus81^5.1, mus309^D2 and spn-A¹ is lethal.

The elevated recombination caused by mus309^D2 is abolished by spn-A¹.

(Johnson-Schlitz and Engels, 2006)

spn-A³/spn-A^093A suppresses the increase deletions resulting from the H{PΔ2-3}HoP2.1 driven of excision of P{hsw^a}sd^wa due to a mus309^D2/mus309^D3 background.

(McVey et al., 2004)

okr^17-11/okr^A19-10 mus309^D2/mus309^D3 double mutants show a synergistic effect on sensitivity to X rays; the sensitivity is increased 40 fold compared to wild-type in double mutants. mus309^D2/mus309^D3 mutants are slightly sensitive to methyl methanesulfonate (MMS). okr^17-11/okr^A19-10 mus309^D2/mus309^D3 double mutants do not show a synergistic effect on sensitivity to MMS.

(Kooistra et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

Df(3R)T-7/Blm^D2 is partially rescued by Blm^hs.PK

(Kusano et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

8657

st¹ Blm^D2 Sb¹ P{Δ2-3}99B/TM6B, Tb¹

94594

y¹ w^67c23; Blm^D2 ry^* rec¹ Ubx^bx-34e P{matα4-GAL-VP16}V37/TM6C, Sb¹; TI{GMR-HMS04515}Gat^eya/In(4)ci^D, ci^D pan^ciD

Kyoto

118751

y¹ w^67c23; Blm^D2 ry^* rec¹ Ubx^bx-34e P{matα4-GAL-VP16}V37/TM6C, Sb¹; TI{GMR-HMS04515}Gat^eya/In(4)ci^D, ci^D pan^ciD

Notes on Origin

Discoverer

Boyd.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Blm^D2

(Bereda et al., 2025, Hartmann et al., 2019, Kuo et al., 2014, Lafave et al., 2014)

(Johnson-Schlitz et al., 2007)

blm^D2

(Thomas et al., 2022)

mus309²

(Szabad, 1998.4.8)

mus309^D2

(Ji et al., 2019, Kohl et al., 2012, Andersen et al., 2011, Andersen et al., 2009, Kappeler et al., 2008, McVey et al., 2007, Song et al., 2007, Trowbridge et al., 2007, Wei and Rong, 2007, Johnson-Schlitz and Engels, 2006, Portin, 2005)

mus309^d2

(Brodsky et al., 2000)

Name Synonyms

Secondary FlyBase IDs

References (26)

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