FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ninaEUS6275
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General Information
Symbol
Dmel\ninaEUS6275
Species
D. melanogaster
Name
FlyBase ID
FBal0050207
Feature type
allele
Associated gene
Dmel\ninaE
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Kumar and Ready, 1995)
Mutagen
ethyl methanesulfonate
(Colley et al., 1995)
Progenitor genotype
Cytology
Description

Amino acid replacement: P184L. Nucleotide substitution: C722T.

(Colley et al., 1995)

Amino acid replacement: P184L.

(Kurada and O'Tousa, 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:19,887,417..19,887,417 [-]
Nucleotide change:

C19887417T

Reported nucleotide change:

C722T|FBrf0080594

Amino acid change:

P184L | ninaE-PA

Reported amino acid change:

P184L|FBrf0080594

(Colley et al., 1995, Kurada and O'Tousa, 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  retinitis pigmentosa
      CEA
      (Colley et al., 1995)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Reduced rhabdomeres.

      (Colley et al., 1995)

      Individuals develop reasonably normal rhabdomeres and none show membrane curtains.

      (Kumar and Ready, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ninaEUS6275 is a suppressor of phenotype of norpAP24

      (Kurada and O'Tousa, 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Molecular lesion not known.

      (Kumar and Ready, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      P184L
      (Bentrop, 1998)
      ninaEP184L
      (Colley et al., 1995)
      ninaEUS6275
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0046178
      References (4)