FlyBase Allele Report: Dmel\Diap1[RING.GMR]

General Information

Symbol

Dmel\Diap1^RING.GMR

Species

D. melanogaster

Name

FlyBase ID

FBal0050601

Feature type

allele

Associated gene

Dmel\Diap1

Associated Insertion(s)

Carried in Construct

P{GMR-DIAP1-RING}

Key Links

Transgenic product class

inframe_deletion

(Hay et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Hay et al., 1995)

Mutagen

in vitro construct

(Hay et al., 1995)

Progenitor genotype

Diap1^GMR.PH

(Hay et al., 1995)

Carried in construct

P{GMR-DIAP1-RING}

Cytology

Description

Deletion leaving Diap1 coding region starting just downstream of the most C-terminal BIR and includes the C-terminal linker and the RING finger.

(Hay et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

Diap1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell death

(Ryoo et al., 2002)

visible

(Ryoo et al., 2002)

Phenotype Manifest In

eye

(Ryoo et al., 2002)

eye-antennal disc

(Hay et al., 1995)

pigment cell

(Ryoo et al., 2002)

Detailed Description

Statement

Reference

Expression of th^RING.GMR results in flies with small eyes that lack pigment cells.

(Ryoo et al., 2002)

Small eye phenotype caused by extra cell death in the third instar eye disc.

(Hay et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Diap1^RING.GMR has visible phenotype, suppressible by eff[+]/eff^D73

(Ryoo et al., 2002)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Diap1^RING.GMR has phenotype, non-enhanceable by Ubc2^k13206

(Ryoo et al., 2002)

Diap1^RING.GMR has phenotype, non-enhanceable by lwr^unspecified

(Ryoo et al., 2002)

Suppressed by

Statement

Reference

Diap1^RING.GMR has eye phenotype, suppressible by eff[+]/eff^D73

(Ryoo et al., 2002)

Diap1^RING.GMR has pigment cell phenotype, suppressible by eff[+]/eff^D73

(Ryoo et al., 2002)

NOT suppressed by

Statement

Reference

Diap1^RING.GMR has phenotype, non-suppressible by Ubc2^k13206

(Ryoo et al., 2002)

Diap1^RING.GMR has phenotype, non-suppressible by lwr^unspecified

(Ryoo et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The eye phenotype caused by expression of th^RING.GMR is suppressed by eff^D73/+ and more pigment cells survive.

(Ryoo et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Diap1^RING.GMR

th^RING.GMR

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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