Lateral glial cells are present but they fail to organise into the regular pattern seen in wild type embryos. In the CNS of stage 16 embryos the number of lateral glial cells is reduced by about 20%. Midline glial cells are still specified but fail to properly differentiate and instead of migrating between the two segmental commissures that remain anterior to the commissures which subsequently appear fused. In stage 16 embryos the midline glial cells start to degenerate and are cleared from the nervous system. pnt ttk double mutant flies display an additive CNS phenotype combining characteristics of both phenotypic traits.
Defect in embryonic PNS development: gain of neurons, outer support cells are transformed into the lineage-related neuron and glia.