paralytic | heat sensitive (with stmA1)
Paralysis at 38oC over stmA1 and recovery at 24oC.
Unhatched embryos exhibit deletions in the anterior dorsal cuticle overlying the head and cephalopharyngeal skeleton, deletions in the cephalopharyngeal skeleton, poorly differentiated ventral cuticle denticles but no effect on the posterior spiracles and filzkorper. The abnormalities range from weak to strong among embryos of the same genotype. The brain lobes are enlarged and the ventral nerve cord expanded. Morphology of the ectodermal cells of the neurogenic region are also disturbed, the regular palisade like arrangement of wild type epidermal primordia is lost. The presumptive foregut and head region were disrupted and there is no distinct proctodeum, foregut lumen, clypeolabrum or pharynx. The amnioserosa is absent and dorsal closure is incomplete. Germ band retraction is delayed and often incomplete.
Group I allele.
Allelic series based on strength of the paralytic phenotype: stmA2 > stmA1 > stmA7 > stmA12.