FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\prd+t18
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General Information
Symbol
Dmel\prd+t18
Species
D. melanogaster
Name
FlyBase ID
FBal0056286
Feature type
allele
Associated gene
Dmel\prd
Associated Insertion(s)
Carried in Construct
P{prd-SN20}
Also Known As
prd-SN20
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Gutjahr et al., 1994)
wild_type
(Gutjahr et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Gutjahr et al., 1994)
wild_type
(Gutjahr et al., 1994)
Mutagen
in vitro construct
(Xue and Noll, 1996, Gutjahr et al., 1994)
Progenitor genotype
Carried in construct
P{prd-SN20}
Cytology
Description

18.7kb genomic fragment that includes the entire prd gene, its transcribed region and adjacent 10.0kb upstream and 5.9kb downstream sequences.

(Xue and Noll, 1996)

18kb NotI-SalI genomic fragment, consisting of the transcribed region, 10kb of upstream and 5kb of 3' flanking prd sequences.

(Gutjahr et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
prd
Encoded product / tool
prd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2L:12,077,252..12,095,465 [-]
Linked to:
SalI-NotI restriction fragment
Comment:

prd escue fragment includes 10 kb of upstream and 5.9 kb of downstream sequences.

(Xue and Noll, 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Single copy of P{prd-SN20} can rescue prd4/Df(2L)Prl transheterozygous embryos to adulthood.

      (Xue and Noll, 1996)

      Allows prd transheterozygotes to survive to adulthood and these adults give rise to fertile offspring.

      (Gutjahr et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      prd+t18 rescues Df(2L)Prl/prd4

      (Xue and Noll, 2002)

      prd+t18 rescues Df(2L)Prl/prd4

      (Xue et al., 2001)

      prd+t18 rescues prd4

      (Xue et al., 2001)

      prd+t18 rescues Df(2L)Prl/prd4

      (Xue and Noll, 2000)
      Comments

      prd4/Df(2L)Prl flies rescued by one copy of prd+t18 survive to adulthood.

      (Xue and Noll, 2002)

      One copy of prd+t18 fully rescues the cuticle phenotype of prd4 homozygous embryos. One copy of prd+t18 fully rescues prd4/Df(2L)Prl animals to adulthood. One copy of prd+t18 fully rescues the fertility of prd4/Df(2L)Prl males.

      (Xue et al., 2001)

      prd4/Df(2L)Prl flies rescued by prd+t18 have accessory glands of normal size.

      (Xue and Noll, 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      prd+t18
      Name Synonyms
      Secondary FlyBase IDs
        References (6)