FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Pax3prd.PX
Open Close
General Information
Symbol
Mmus\Pax3prd.PX
Species
M. musculus
Name
paired promoter construct of Xue
FlyBase ID
FBal0058514
Feature type
allele
Associated gene
Mmus\Pax3
Associated Insertion(s)
Carried in Construct
P{prd-Pax3}
Transgenic product class
cDNA
(Xue and Noll, 1996)
wild_type
(Xue and Noll, 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Xue and Noll, 1996)
wild_type
(Xue and Noll, 1996)
Mutagen
in vitro construct
(Xue and Noll, 1996)
Progenitor genotype
Carried in construct
P{prd-Pax3}
Cytology
Description

NotI-HindIII fragment containing the complete prd cis-regulatory region is fused to an XbaI fragment of the Mmus\Pax3 cDNA encoding the entire coding region, and SacII-NotI fragment of prd downstream sequences.

(Xue and Noll, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
prd
Encoded product / tool
Mmus\Pax3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Mmus\Pax3prd.PX is a suppressor of embryonic/first instar larval cuticle phenotype of prd4

      (Xue et al., 2001)

      Mmus\Pax3prd.PX is a suppressor of cuticle phenotype of Df(2L)Prl/prd4

      (Xue and Noll, 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      One copy of Mmus\Pax3prd.PX partially rescues the cuticle phenotype of prd4 homozygous embryos, while two copies fully rescue the phenotype. Two copies of Mmus\Pax3prd.PX fail to rescue prd4/Df(2L)Prl animals to adulthood. Two copies of Mmus\Pax3prd.PX partially rescue viability of prd10/Df(2L)Prl adults, while one copy fails to rescue prd10/Df(2L)Prl viability.

      (Xue et al., 2001)

      Able to rescue the cuticular phenotype of prd4/Df(2L)Prl transheterozygous embryos. One copy of each P{prd-Gsb} and P{prd-Pax3} gives most efficient rescue of prd transheterozygous embryos to adults, viable adults show distorted abdominal phenotype due to disorganisation of segments.

      (Xue and Noll, 1996)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmus\Pax3prd.PX
      Mus\Pax3prd.PX
      Name Synonyms
      paired promoter construct of Xue
      (Xue and Noll, 1996)
      Secondary FlyBase IDs
        References (3)