FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\B5228
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General Information
Symbol
Dmel\B5228
Species
D. melanogaster
Name
FlyBase ID
FBal0059381
Feature type
allele
Associated gene
Dmel\B52
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Peng and Mount, 1995, Ring and Lis, 1994)
Progenitor genotype
P{lacW}Hrb87FY1217
(Peng and Mount, 1995, Ring and Lis, 1994)
Caused by aberration
Df(3R)B5228
Cytology
Description

Imprecise excision of the P{lacW} insertion of Hrb87FY1217.

(Peng and Mount, 1995)

Deletion extending from the 5' noncoding region of Hrb87F to the 5' half of the B52 coding region (including the intergenic region between Hrb87F and B52). Some part of the P{lacW} element insertion present in Hrb87FY1217 remains.

(Ring and Lis, 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die as first or second instar larvae. In addition, homozygotes have an extended second instar larval period of 3-5 days.

      (Ring and Lis, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      B5228 is partially rescued by B52+t10

      (Ring and Lis, 1994)
      Comments

      B52+t10 rescues the lethality of homozygous B5228 flies. Homozygous B5228 flies carrying B52+t10 have low fertility.

      (Ring and Lis, 1994)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      βTub56D, Hsp83, Sxl, Ubx and Ddc pre-mRNAs are spliced in B5228 mutant larvae, indicating that B52 is not required for all splicing in vivo.

      (Ring and Lis, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      B5228
      (Ustaoglu et al., 2019, Juge et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)