FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fs(1)K10unspecified
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General Information
Symbol
Dmel\fs(1)K10unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0060403
Feature type
allele
Associated gene
Dmel\fs(1)K10
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        fs(1)K10unspecified mutants lay eggs containing a mass of chorionic material instead of two dorsal appendages.

        (Barth et al., 2011)

        Homozygous mutant eggs are dorsalised.

        (Chang et al., 2001)

        Eggs derived from homozygous females are dorsalised, 99% having dorsal appendage material extending around the lateral and ventral side of the egg. Eggs derived from fs(1)K10unspecified; okrAA/Df(2L)JS17, fs(1)K10unspecified; grk3/+ or fs(1)K10unspecified; spn-B2/spn-B1 females show a broad spectrum of phenotypes ranging from completely dorsalised to completely ventralised.

        (Ghabrial et al., 1998)

        Homozygous females lay dorsalised eggs. This phenotype is not altered if the females also carry vas6356-001/vas6356-005.

        (Tinker et al., 1998)

        Fate-mapping experiments show that fs(1)K10unspecified embryos do possess dorso-ventral polarity, but the dorsoventral and anteroposterior axes lie parallel to each other in these mutant embryos.

        (Haenlin et al., 1995)

        Homozygous females lay eggs with abnormal dorsal appendages.

        (Mohler, 1977)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhanced by
        Statement
        Reference

        fs(1)K10unspecified has egg | ventral phenotype, non-enhanceable by orbmel/orbmel

        (Chang et al., 2001)
        Suppressed by
        Statement
        Reference

        fs(1)K10unspecified has phenotype, suppressible by grk3

        (Haenlin et al., 1995)
        NOT suppressed by
        Statement
        Reference

        fs(1)K10unspecified has egg | ventral phenotype, non-suppressible by orbmel/orbmel

        (Chang et al., 2001)
        Other
        Statement
        Reference

        fs(1)K10unspecified, orbmel has egg | ventral phenotype

        (Chang et al., 2001)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        orbmel/orbmel, fs(1)K10unspecified/fs(1)K10unspecified eggs are dorsalised.

        (Chang et al., 2001)

        The misorientation of the dorsoventral and anteroposterior axes is partly corrected if the number of wild-type copies of grk is reduced (using grk3).

        (Haenlin et al., 1995)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        fs(1)K10
        (Barth et al., 2011)
        fs(1)K10unspecified
        unspecified
        (Haenlin et al., 1995)
        Name Synonyms
        Secondary FlyBase IDs
          References (13)